"Maybe there's a higher work ethic for all of us just because you know you have to work a little harder coming from a small school," said Allen, who had a franchiserecord 22 sacks a year ago. "But I'm a firm believer that in football you get out of it what you put into it. If you're willing to learn techniques and learn assignments and realize you did something good enough to get you here, you'll be fine.Although the majority of ALS cases are sporadic (sALS), about 10 are inherited in a dominant manner (fALS) (Boillee et al, 2006; Valdmanis and Rouleau, 2008). Although these genes account for only a small number of fALS cases, their gene products seem to have a crucial function in the pathogenesis of the majority of ALS cases, including sALS, as well as the related disorder frontotemporal lobar degeneration with ubiquitinpositive inclusions (FTLDU). Both neurodegenerative diseases are characterized by the presence of neuronal and/or glial TDP43 or FUS inclusions.