"I think with everything that's gone on, the sooner I can get in here the better. It's been a long time, but I'm ready to get to work. I've been anxious," he said.Notch activity converges on mTOR and Rictor to regulate neglectinduced deathThe depletion of mTOR attenuated NICmediated inhibition of apoptosis (Figure 4a), positioning mTOR as an intermediate in the pathway. The two complexes of mTOR mTORC1 and mTORC2 are distinguished by dependence on the proteins Raptor and Rictor, respectively. To investigate the roles of mTORC1 and mTORC2 in this pathway, the requirement for Raptor or Rictor in the antiapoptotic function of Notch was assessed.

As you've been preparing to start college, you've likely been thinking of the ways both good and bad that it is going to be different than high school. You're going to be living in a new place with a roommate who you've stalked so hard on Facebook that you know where she spent Christmas vacation in 2002. You're going to be